PUBLICATIONS: Sibylle Brenner

2020

Brenner, S., F. Berger, L. Rao, M. P. Nicholas, and A. Gennerich. Force production of human cytoplasmic dynein is limited by its processivity. 2020. Sci. Adv. 6:eaaz4295. [pdf]

2015

Nicholas, M. P., F. Berger, L. Rao, S. Brenner, C. Cho, and A. Gennerich. Cytoplasmic dynein regulates its attachment to microtubules via nucleotide state-switched mechanosensing at multiple AAA domains. 2015. Proc. Natl. Acad. Sci. USA, 12:6371-6376. [pdf]

Nicholas, M. P.*, P. Hook*, S. Brenner, C. Lazar, R. B. Vallee#, and A. Gennerich#. Control of cytoplasmic dynein force production and processivity by its C-terminal domain. 2015. Nat. Commun., 6:6206 (*: Co-first authors; #: co-corresponding authors). [pdf]

2013

Rao, L.*, E. M. Romes*, M. P. Nicholas, S. Brenner, T. Ashutosh, A. Gennerich#, and K. C. Slep#. The yeast dynein dyn2-pac11 complex is a dynein dimerization/processivity factor: structural and single molecule characterization. 2013. Mol. Biol. Cell (*: co-first authors; #: co-corresponding authors). [pdf]

2011

Leferink, N. G., C. R. Pudney, S. Brenner, D. J. Heyes, R. R. Eady, S. S. Hasnain, S. Hay, S. E. Rigby, and N. S. Scrutton. Gating mechanisms for biological electron transfer: Integrating structure with biophysics reveals the nature of redox control in cytochrome P450 reductase and copper-dependent nitrite reductase. 2011. FEBS Lett. 586:578-584. [pdf]

2010

Hay, S., S. Brenner, B. Khara, A. M. Quinn, S. E. Rigby, and N. S. Scrutton. Nature of the energy landscape for gated electron transfer in a dynamic redox protein. 2010. J. Am. Chem. Soc. 132:9738-9745. [pdf]

2009

Brenner, S., D. J. Heyes, S. Hay, M. A. Hough, R. R. Eady, S. S. Hasnain, and N. S. Scrutton. Demonstration of proton-coupled electron transfer in copper-containing nitrite reductases. 2009. J. Biol. Chem. 284:25973-25983. [pdf]

Brenner, S., S. Hay, and N. S. Scrutton. Ionic Strength Dependence of the Heating Time in T-Jump Instrument TJ-64. 2009. Hi-Tech Scientific AN.020.T64.

2008

Wohlgemuth, I., S. Brenner, M. Beringer, and M. V. Rodnina. Modulation of the rate of peptidyl transfer on the ribosome by the nature of substrates. 2008. J. Biol. Chem. 283:32229-32235. [pdf]

Brenner, S., S. Hay, A. W. Munrow, and N. S. Scrutton. Inter-flavin electron transfer in cytochrome P450 reductase - effects of solvent and pH identify hidden complexity in mechanism. 2008. FEBS J. 275:4540-4557. [pdf]

2007

Brenner, S., S. Hay, H. M. Girvan, A. W. Munro, and N. S. Scrutton. Conformational dynamics of the cytochrome P450 BM3/N-palmitoylglycine complex: the proposed "proximal-distal" transition probed by temperature-jump spectroscopy. 2007. J. Phys. Chem. B 111:7879-7886. [pdf]

2006

Brenner, S., S. Hay, and N. S. Scrutton. Temperature calibration of T-Jump Instrument TJ-64 using Tris/Phenol Red. 2006. Hi-Tech Scientific AN.019.T64.